Animated Start Guide

Start the regimen with a clear, guided plan

A visual walkthrough of the Vitamin D3 Anti-Inflammatory Regimen, taken straight from the Quick Start Guide and laid out in the order people actually need it: prepare, test, load, retest then maintain.

Based on the Quick Start Guide, September 25, 2023

Do this with medical supervision

The guide asks you to discuss this protocol with a primary care physician or neurologist before starting, especially if you have existing medical conditions or take prescribed medications. The lab tests below are the safety framework for the whole regimen.

View Blood Test Guide
The Sequence

Seven steps from decision to maintenance

Each step builds on the one before it. Scroll through to watch the plan come together, then keep the downloadable guides nearby for the full detail.

1
Before supplements

Talk to your doctor and order baseline labs

Bring the guide to your PCP or neurologist and ask for baseline blood tests before you start: serum 25-Hydroxyvitamin D3, calcium and parathyroid hormone. This first set of results becomes your baseline.

25(OH)D3 Calcium PTH
2
Create a baseline

Start a headache log

Track attack timing, duration, severity and treatments so you can see what changes once you start. A simple paper log is enough, or you can use a free cluster headache tracking app such as My Clusters.

3
Daily foundation

Assemble vitamin D3 and the cofactors

The Quick Start Guide pairs vitamin D3 with a set of daily cofactors. With the exception of D3, which can be daily or weekly, every cofactor is taken daily.

  • Vitamin D3daily or weekly
  • Mature multivitamin1 a day
  • Magnesium400 mg a day
  • Omega-3 fish oil2 a day
  • Methyl folate + B complex1 a day
  • Vitamin K2 complex1 a day
4
Supervised loading

Run the supervised loading schedule from the guide

The guide uses a total loading dose of 600,000 IU of vitamin D3, most often spread over either 12 days at 50,000 IU a day or 6 days at 100,000 IU a day. Both schedules are described as equally effective, and the cofactors are taken daily throughout.

12 days 50,000 IU / day
6 days 100,000 IU / day
600,000 IU total loading dose
While loading, the guide adds: double the magnesium to 400 mg with breakfast and 400 mg with the evening meal, and hydrate with about 2.5 litres of water a day. If there is no change in cluster headache after 5 days of loading, it suggests starting the Antihistamine Full Monty supplements while continuing to load. There is separate body-weight guidance for children or adults under 115 lb (52 kg), and loading should be done under physician supervision.
5
Safety check

Retest your bloods after loading

The guide asks for follow-up assays of 25(OH)D3, calcium and PTH either 15 days after completing the 100,000 IU a day schedule or 30 days after starting the 50,000 IU a day schedule.

What the labs are looking for: a rise in 25(OH)D3 of about 55 to 60 ng/mL above your baseline, serum calcium within its normal reference range and PTH lower than baseline. Your doctor uses these results to guide the next step.
6
Long-term pattern

Move to maintenance and keep cofactors daily

After loading, the guide drops back to a starting maintenance dose of 10,000 IU a day, or 50,000 IU a week with the capsule form, then adjusts with your doctor using your symptoms and lab results.

Maintenance is ongoing. The guide treats this as a long-term pattern, not a cure that can simply be stopped. Cofactors continue daily, and your doctor may move the dose up or down based on response and bloods.
7
Help the community

Take the survey once you have results

When you have your first follow-up labs and early response data, the guide asks patients to complete the survey so the wider community can keep learning from real outcomes.

Open the Survey
Keep Nearby

Use this walkthrough with the original guides

This page is a teaching aid. The downloadable guides remain the source documents for the complete protocol, brand notes, lab details and safety context.

Quick Start Guide

Condensed guide with the practical starting sequence, loading schedules, cofactors and retesting instructions.

Download Quick Start Guide

Full Reference Guide

Detailed protocol for patients and healthcare providers, including the broader background and clinical discussion.

Download Full Reference Guide